Trazodone - Off-Label for Menopausal Sleep Disturbances

About

Trazodone is an antidepressant FDA-approved for major depressive disorder but frequently prescribed off-label at lower doses as a sleep aid for women experiencing insomnia related to menopause, particularly when hormonal fluctuations or hot flashes disrupt sleep patterns.

Efficacy

Limited clinical trial data specific to menopausal insomnia; observational evidence and studies in general insomnia suggest effectiveness for sleep initiation and maintenance

Targets Symptoms