Spironolactone - Off-Label for Menopausal Acne and Hirsutism

About

Spironolactone is a potassium-sparing diuretic and aldosterone antagonist FDA-approved for hypertension, heart failure, and edema, but often prescribed off-label for managing hormone-related acne and excess facial/body hair that can occur during the hormonal shifts of menopause.

Efficacy

Clinical studies show significant improvement in adult female acne and reduction in hirsutism through anti-androgenic effects

Targets Symptoms