Escitalopram (Lexapro) - Off-Label for Hot Flashes and Mood Symptoms

About

Escitalopram is a selective serotonin reuptake inhibitor (SSRI) FDA-approved for depression and anxiety disorders but frequently prescribed off-label for managing hot flashes and mood symptoms during menopause, particularly for women who cannot take hormone therapy.

Efficacy

Clinical trials show 55% reduction in hot flash frequency compared to 36% with placebo; significant improvement in hot flash severity and bother

Targets Symptoms