Citalopram (Celexa) - Off-Label for Hot Flashes

About

Citalopram is a selective serotonin reuptake inhibitor (SSRI) FDA-approved for depression but commonly prescribed off-label for managing hot flashes during menopause, with demonstrated efficacy in clinical trials particularly for women who cannot take hormone therapy.

Efficacy

Clinical trials show 49-55% reduction in hot flash frequency compared to 23-36% with placebo

Targets Symptoms